GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ldhA3) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.215 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ldhA3) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.215 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ldhA3) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.215 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ldhA3) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.215 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (thrC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.2.3.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (idnO) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.69 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gutQ1) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.3.1.13 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aas) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aas) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aas) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aas) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aas) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (wecF2) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aas) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aas) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aas) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aas) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (goaG) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.6.1.19 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (adhE) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.2.1.10 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (accA) PROTEIN_ASSOCIATION: SUBSYSTEM: Fatty_Acid_biosynthesis PROTEIN_CLASS: 6.4.2.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (accA and accB and accC2 and accD) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: 6.4.1.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2373) or (aceK) PROTEIN_ASSOCIATION: SUBSYSTEM: Aminosugars_metabolism PROTEIN_CLASS: 3.1.3.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2373) or (aceK) PROTEIN_ASSOCIATION: SUBSYSTEM: Thiamine_metabolism PROTEIN_CLASS: 3.1.3.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nagE and ptsH and ptsI) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (argB) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.7.2.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (argA) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.3.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aceE and ilvB2 and ilvH) or (aceE and ilvB2 and ilvM) or (aceE and ilvB2 and ilvN) or (aceE and ilvG and ilvH) or (aceE and ilvG and ilvM) or (aceE and ilvG and ilvN) or (aceE and ilvI and ilvH) or (aceE and ilvI and ilvM) or (aceE and ilvI and ilvN) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_leucine_and_isoleucine_metabolism PROTEIN_CLASS: 1.2.4.1 2.2.1.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ackA) PROTEIN_ASSOCIATION: SUBSYSTEM: Pyruvate_metabolism PROTEIN_CLASS: 2.7.2.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aceE and ilvB2 and ilvH) or (aceE and ilvB2 and ilvM) or (aceE and ilvB2 and ilvN) or (aceE and ilvG and ilvH) or (aceE and ilvG and ilvM) or (aceE and ilvG and ilvN) or (aceE and ilvI and ilvH) or (aceE and ilvI and ilvM) or (aceE and ilvI and ilvN) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_leucine_and_isoleucine_metabolism PROTEIN_CLASS: 1.2.4.1 2.2.1.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (wecG) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (manX1 and manY and manZ and ptsH and ptsI) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: 2.7.3.9 and EC-2.7.1.69 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nanT) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dapA1) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.1.3.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: 2.3.1.38 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (argE2) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 3.5.1.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (tam) PROTEIN_ASSOCIATION: SUBSYSTEM: Unassigned PROTEIN_CLASS: 2.1.1.144 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (acnA) or (acnB) PROTEIN_ASSOCIATION: SUBSYSTEM: Citrate_Cycle_(TCA) PROTEIN_CLASS: 4.2.1.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP0172) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.6.1.11 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (acpS) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.8.7 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (acs) PROTEIN_ASSOCIATION: SUBSYSTEM: Pyruvate_metabolism PROTEIN_CLASS: 6.2.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (acs) PROTEIN_ASSOCIATION: SUBSYSTEM: Propanoate_metabolism PROTEIN_CLASS: 6.2.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pabC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.1.3.38 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pabA and pabB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.6.1.85 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (adhE) PROTEIN_ASSOCIATION: SUBSYSTEM: Pyruvate_metabolism PROTEIN_CLASS: Undetermined LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (adhE) PROTEIN_ASSOCIATION: SUBSYSTEM: butanoate_metabolism PROTEIN_CLASS: 1.2.1.10 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (adk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (adk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (adk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (speD) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 4.1.1.50 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cyaB) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 4.6.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nupC1) or (nupC2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (apt1 and hpt) or (apt2 and hpt) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.4.2.7 2.4.2.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cysC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cysteine_Metabolism PROTEIN_CLASS: 2.7.1.25 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (purB) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 4.3.2.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (purB) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 4.3.2.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (purA) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 6.3.4.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nagA) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.5.1.25 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (rfaD) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 5.1.3.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (argC) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.2.1.38 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mtn) PROTEIN_ASSOCIATION: SUBSYSTEM: Methionine_Metabolism PROTEIN_CLASS: 3.2.2.9 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (purH) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.1.2.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (purE) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 4.1.1.21 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (purK) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ddl) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.3.2.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (alr) PROTEIN_ASSOCIATION: SUBSYSTEM: Alanine_and_aspartate_metabolism PROTEIN_CLASS: 5.1.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (alr) PROTEIN_ASSOCIATION: SUBSYSTEM: Alanine_and_aspartate_metabolism PROTEIN_CLASS: 5.1.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (livF and livG and livH and livK2 and livM and livK1 and livM2 and livG1 and livF1) or (livF and livG and livH and livK2 and livM1 and livK1 and livM2 and livG1 and livF1) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ansP3) PROTEIN_ASSOCIATION: SUBSYSTEM: Putative_Transporters PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (adhC) or (adhE) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (uxaA) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.2.1.7 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (malQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.4.1.25 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (malQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.4.1.25 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (malQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.4.1.25 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (malQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.4.1.25 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nanE) PROTEIN_ASSOCIATION: SUBSYSTEM: Putative PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nagC7) PROTEIN_ASSOCIATION: SUBSYSTEM: Putative PROTEIN_CLASS: 2.7.1.60 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ubiE) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.1.1- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (thiC and thiD) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.49 and ThiC LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (trpD) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_Tryptophan_and_Phenylalanine_Metabolism PROTEIN_CLASS: 2.4.2.18 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (trpE2 and trpG) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_Tryptophan_and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.1.3.27 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (bioF) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.3.1.47 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (apaH) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.6.1.41 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (apaH) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ribD) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.1.1.193 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (apt1) or (apt2) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_metabolism PROTEIN_CLASS: 2.4.2.7 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (araB1) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_and_Glucoronate_Interconverstion PROTEIN_CLASS: 2.7.1.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (araA) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.3.1.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (araF and araG and araH and rbsD1) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (adiA) or (speA) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 4.1.1.19 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (potE3) PROTEIN_ASSOCIATION: SUBSYSTEM: Putative_Transporters PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (argH) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 4.3.2.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (argG) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 6.3.4.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (artI3 and artJ and artM and artP and artQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aroQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Shikimate_cycle PROTEIN_CLASS: 4.2.1.10 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (asd1) or (asd2) PROTEIN_ASSOCIATION: SUBSYSTEM: Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 1.2.1.11 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ansA) or (ansB) PROTEIN_ASSOCIATION: SUBSYSTEM: Alanine_and_aspartate_metabolism PROTEIN_CLASS: 3.5.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (asnB) PROTEIN_ASSOCIATION: SUBSYSTEM: Alanine_and_aspartate_metabolism PROTEIN_CLASS: 6.3.5.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (asnA) PROTEIN_ASSOCIATION: SUBSYSTEM: Alanine_and_aspartate_metabolism PROTEIN_CLASS: 6.3.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glnQ1 and artI2 and artM1) or (glnQ1 and artI2 and artM2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ansP3) or (ansP2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (panD) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.1.1.11 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pyrB and pyrI) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.1.3.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aspC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cysteine_Metabolism PROTEIN_CLASS: 2.6.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aspC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cysteine_Metabolism PROTEIN_CLASS: 2.6.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aspC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cysteine_Metabolism PROTEIN_CLASS: 2.6.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aspC) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.6.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (lysC2) or (metL) or (thrA) PROTEIN_ASSOCIATION: SUBSYSTEM: Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 2.7.2.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nadB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.4.3.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nadB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.4.3.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nadB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.4.3.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nadB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.4.3.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aspA) PROTEIN_ASSOCIATION: SUBSYSTEM: Alanine_and_aspartate_metabolism PROTEIN_CLASS: 4.3.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aspC) PROTEIN_ASSOCIATION: SUBSYSTEM: Alanine_and_aspartate_metabolism PROTEIN_CLASS: 2.6.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glnH1 and gltJ1 and gltK and gltL) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gltP) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gltP) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dcuA) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (astA) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.3.1.109 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (atpM) PROTEIN_ASSOCIATION: SUBSYSTEM: Unassigned PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hisG) PROTEIN_ASSOCIATION: SUBSYSTEM: Histidine_Metabolism PROTEIN_CLASS: 2.4.2.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (atpA and atpB and atpC and atpD and atpE and atpF and atpG and atpH) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 3.6.3.14 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (betA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycine_metabolism PROTEIN_CLASS: 1.1.99.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (betB) PROTEIN_ASSOCIATION: SUBSYSTEM: Unassigned PROTEIN_CLASS: 1.2.1.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (betB) PROTEIN_ASSOCIATION: SUBSYSTEM: Unassigned PROTEIN_CLASS: 1.2.1.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (betA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycine_metabolism PROTEIN_CLASS: 1.1.99.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (bgaB) or (lacZ) PROTEIN_ASSOCIATION: SUBSYSTEM: Galactose_metabolism PROTEIN_CLASS: 3.2.1.23 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (bgaB) or (lacZ) PROTEIN_ASSOCIATION: SUBSYSTEM: Galactose_metabolism PROTEIN_CLASS: 3.2.1.23 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (bgaB) or (lacZ) PROTEIN_ASSOCIATION: SUBSYSTEM: Sphingolipid_metabolism PROTEIN_CLASS: 3.2.1.23 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (bglA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 3.2.1.86 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (birA) PROTEIN_ASSOCIATION: SUBSYSTEM: Biotin_Metabolism PROTEIN_CLASS: 6.3.4.15 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (birA) PROTEIN_ASSOCIATION: SUBSYSTEM: Biotin_Metabolism PROTEIN_CLASS: 6.3.4.15 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (bisC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (bisC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (bioB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.8.1.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (btuE) PROTEIN_ASSOCIATION: SUBSYSTEM: glutathione_metabolism PROTEIN_CLASS: 1.11.1.9 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (btuR) PROTEIN_ASSOCIATION: SUBSYSTEM: Porphyrin_metabolism PROTEIN_CLASS: 2.5.1.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (katA) or (katG) PROTEIN_ASSOCIATION: SUBSYSTEM: Unassigned PROTEIN_CLASS: 1.11.1.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (btuR) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.5.1.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (btuB and btuC2 and btuD and fecB1) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (btuR) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.5.1.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (carA and carB) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 6.3.5.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cdh) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: 3.6.1.26 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ipk) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.148 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cdsA) or (cdsA1) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: 2.7.7.41 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (celA and celB and celC and ptsH and ptsI) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: 2.7.3.9 and EC-2.7.1.69 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (proV2 and proW3 and proX) PROTEIN_ASSOCIATION: SUBSYSTEM: Putative_Transporters PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (betT2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pheA) or (pheA2) or (tyrA) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_Tryptophan_and_Phenylalanine_Metabolism PROTEIN_CLASS: 5.4.99.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aroC) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_Tryptophan_and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.2.3.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ubiC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.1.3.40 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (citE2) PROTEIN_ASSOCIATION: SUBSYSTEM: Citrate_Cycle_(TCA) PROTEIN_CLASS: 4.1.3.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cls) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycerophospholipid_metabolism PROTEIN_CLASS: 2.7.8.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cls) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycerophospholipid_metabolism PROTEIN_CLASS: 2.7.8.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (coaA) PROTEIN_ASSOCIATION: SUBSYSTEM: Pantothenate_and_CoA_metabolism PROTEIN_CLASS: 2.7.1.33 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (coaA) PROTEIN_ASSOCIATION: SUBSYSTEM: Pantothenate_and_CoA_metabolism PROTEIN_CLASS: 2.7.1.33 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cobB) PROTEIN_ASSOCIATION: SUBSYSTEM: Nicotinate_and_nicotinamide_metabolism PROTEIN_CLASS: 3.5.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cobB) PROTEIN_ASSOCIATION: SUBSYSTEM: Pantothenate_and_CoA_metabolism PROTEIN_CLASS: 3.5.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (codA) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.5.4.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cpdB) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_metabolism PROTEIN_CLASS: 3.1.4.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cpdB) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_metabolism PROTEIN_CLASS: 3.1.4.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cpdB) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_metabolism PROTEIN_CLASS: 3.1.4.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cpdB) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_metabolism PROTEIN_CLASS: 3.1.4.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hemF) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.3.3.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (betT2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gltA) PROTEIN_ASSOCIATION: SUBSYSTEM: Citrate_Cycle_(TCA) PROTEIN_CLASS: 2.3.3.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (codA) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.5.4.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fUI1) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pyrG) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 6.3.4.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cyaB) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 4.6.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glpE) PROTEIN_ASSOCIATION: SUBSYSTEM: Unassigned PROTEIN_CLASS: 2.8.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cysC) PROTEIN_ASSOCIATION: SUBSYSTEM: Selenoamino_acid_metabolism PROTEIN_CLASS: 2.7.1.25 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cysI and cysJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Selenoamino_acid_metabolism PROTEIN_CLASS: 1.8.1.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cysN) PROTEIN_ASSOCIATION: SUBSYSTEM: Selenoamino_acid_metabolism PROTEIN_CLASS: 2.7.7.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cysK1) or (cysK2) or (cysM) or (cysM2) PROTEIN_ASSOCIATION: SUBSYSTEM: Cysteine_Metabolism PROTEIN_CLASS: 2.5.1.47 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (metC2) or (metC3) PROTEIN_ASSOCIATION: SUBSYSTEM: Methionine_Metabolism PROTEIN_CLASS: 4.4.1.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (artM4 and fliY and glnQ2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cydA and cydB) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.10.3.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cyoA and cyoB and cyoC and cyoD and cyoE) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.10.3.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cdd) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.5.4.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (udk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.1.48 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nupC1) or (nupC2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cmk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.14 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cmk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.14 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ptsG) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dadA1) PROTEIN_ASSOCIATION: SUBSYSTEM: Alanine_and_aspartate_metabolism PROTEIN_CLASS: 1.4.99.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dadA1) PROTEIN_ASSOCIATION: SUBSYSTEM: Nitrogen_Metabolism PROTEIN_CLASS: 1.4.99.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dadA1) PROTEIN_ASSOCIATION: SUBSYSTEM: Nitrogen_Metabolism PROTEIN_CLASS: 1.4.99.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dadA1) PROTEIN_ASSOCIATION: SUBSYSTEM: Phenylalanine_Metabolism PROTEIN_CLASS: 1.4.99.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nupC1) or (nupC2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ansP3) or (cycA) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dalD) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_and_Glucoronate_Interconverstion PROTEIN_CLASS: 1.1.1.11 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (lysA) PROTEIN_ASSOCIATION: SUBSYSTEM: Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 4.1.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dapF) PROTEIN_ASSOCIATION: SUBSYSTEM: Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 5.1.1.7 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ribB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: RIBB LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (bioD) or (bioD2) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 6.3.3.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dcd) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.5.4.13 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dcd) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.5.4.13 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cdd) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.5.4.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nupC1) or (nupC2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (kdgK) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.45 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ddhA) PROTEIN_ASSOCIATION: SUBSYSTEM: Starch_and_sucrose_metabolism PROTEIN_CLASS: 2.7.7.33 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ddhA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.7.7.33 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (wcaG1) PROTEIN_ASSOCIATION: SUBSYSTEM: Starch_and_sucrose_metabolism PROTEIN_CLASS: 4.2.1.45 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aroF) or (aroG) or (aroH) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_Tryptophan_and_Phenylalanine_Metabolism PROTEIN_CLASS: 2.5.1.54 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (deoD) PROTEIN_ASSOCIATION: SUBSYSTEM: Nicotinate_and_nicotinamide_metabolism PROTEIN_CLASS: 2.4.2.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (deoD) PROTEIN_ASSOCIATION: SUBSYSTEM: Nicotinate_and_nicotinamide_metabolism PROTEIN_CLASS: 2.4.2.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gmk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dgkA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycerophospholipid_metabolism PROTEIN_CLASS: 2.7.1.107 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ilvD) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_leucine_and_isoleucine_metabolism PROTEIN_CLASS: 4.2.1.9 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ilvD) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_leucine_and_isoleucine_metabolism PROTEIN_CLASS: 4.2.1.9 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dapB) PROTEIN_ASSOCIATION: SUBSYSTEM: Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 1.3.1.26 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dapA) PROTEIN_ASSOCIATION: SUBSYSTEM: Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 4.2.1.52 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (folA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.5.1.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (folC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 6.3.2.12, EC-6.3.2.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (menA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.5.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (folB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.1.2.25 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pyrD) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 1.3.3.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pyrD) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 1.3.3.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pyrC) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 3.5.2.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ribD) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 3.5.4.26 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (folP) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.5.1.15 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (eno) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_Tryptophan_and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.2.1.10, Ec-4.2.1.11 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aroB) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_Tryptophan_and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.2.3.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dkgA and dkgB) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.274 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ldhA3) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.215 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ldhA3) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.215 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ispA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.5.1.10 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ispH) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.17.1.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ubiG) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.1.1.64 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dmsA1 and dmsA2 and dmsB1 and dmsC1) or (dmsA1 and dmsA2 and dmsB2 and dmsC1) or (dmsA1 and dmsC2 and dmsB1 and dmsC1) or (dmsA1 and dmsC2 and dmsB2 and dmsC1) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.8.99.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dmsA1 and dmsA2 and dmsB1 and dmsC1) or (dmsA1 and dmsA2 and dmsB2 and dmsC1) or (dmsA1 and dmsC2 and dmsB1 and dmsC1) or (dmsA1 and dmsC2 and dmsB2 and dmsC1) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.8.99.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mgtA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 3.6.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mgtA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 3.6.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (coaE) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.24 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (apbA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.1.1.169 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (deoC1) or (deoC2) or (deoC3) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.1.2.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ansP3) or (cycA) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2249) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.9 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP1975) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.2.21 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (deoD) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.4.2.1, 2.4.2.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nupC1) or (nupC2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dut) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.6.1.23 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dxr) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.1.1.267 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dxs) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.2.1.7 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (xylB1) or (xylB2) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (epd) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.2.1.72 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (eda) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_Phosphate_Cycle PROTEIN_CLASS: 4.1.2.14 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (eda) PROTEIN_ASSOCIATION: SUBSYSTEM: Glyoxylate_and_dicarboxylate_metabolism PROTEIN_CLASS: 4.1.3.16 and 4.1.3.14 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (edd) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_Phosphate_Cycle PROTEIN_CLASS: 4.2.1.12 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (msbB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (msbB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.3.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (msbB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (eno) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 4.2.1.11 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (accC2) PROTEIN_ASSOCIATION: SUBSYSTEM: Fatty_Acid_biosynthesis PROTEIN_CLASS: 6.3.4.14 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fadB) or (fadJ) PROTEIN_ASSOCIATION: SUBSYSTEM: propanoate_metabolism PROTEIN_CLASS: 4.2.1.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fadB) or (fadJ) PROTEIN_ASSOCIATION: SUBSYSTEM: butanoate_metabolism PROTEIN_CLASS: 4.2.1.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fadB) or (fadJ) PROTEIN_ASSOCIATION: SUBSYSTEM: butanoate_metabolism PROTEIN_CLASS: 1.1.1.35 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fadB) or (fadJ) PROTEIN_ASSOCIATION: SUBSYSTEM: butanoate_metabolism PROTEIN_CLASS: 5.1.2.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fadB) or (fadJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_Leucine_isoleucine_metabolism PROTEIN_CLASS: 4.2.1.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fadB) or (fadJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_Leucine_isoleucine_metabolism PROTEIN_CLASS: 1.1.1.35 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fadB) or (fadJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_Leucine_isoleucine_metabolism PROTEIN_CLASS: 4.2.1.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fadB) or (fadJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_Leucine_isoleucine_metabolism PROTEIN_CLASS: 4.2.1.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fadB) or (fadJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Limonene_and_Pinene_degradation PROTEIN_CLASS: 4.2.1.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fadB) or (fadJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Limonene_and_Pinene_degradation PROTEIN_CLASS: 4.2.1.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fAA1 and fadA and fadB and fadE) or (fAA1 and fadA and fadJ and fadE) or (fAA1 and fadI and fadB and fadE) or (fAA1 and fadI and fadJ and fadE) or (fadD and fadA and fadB and fadE) or (fadD and fadA and fadJ and fadE) or (fadD and fadI and fadB and fadE) or (fadD and fadI and fadJ and fadE) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: 2.3.1.16 and EC-1.1.1.35 and EC-4.2.1.17 and EC-1.3.99.- and 6.2.1.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fAA1 and fadA and fadB and fadE) or (fAA1 and fadA and fadJ and fadE) or (fAA1 and fadI and fadB and fadE) or (fAA1 and fadI and fadJ and fadE) or (fadD and fadA and fadB and fadE) or (fadD and fadA and fadJ and fadE) or (fadD and fadI and fadB and fadE) or (fadD and fadI and fadJ and fadE) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: 2.3.1.16 and EC-1.1.1.35 and EC-4.2.1.17 and EC-1.3.99.- and 6.2.1.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fAA1 and fadA and fadB and fadE) or (fAA1 and fadA and fadJ and fadE) or (fAA1 and fadI and fadB and fadE) or (fAA1 and fadI and fadJ and fadE) or (fadD and fadA and fadB and fadE) or (fadD and fadA and fadJ and fadE) or (fadD and fadI and fadB and fadE) or (fadD and fadI and fadJ and fadE) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: 2.3.1.16 and EC-1.1.1.35 and EC-4.2.1.17 and EC-1.3.99.- and 6.2.1.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fadB and fadE) or (fadJ and fadE) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.35 and EC-4.2.1.17 and EC-1.3.99.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fba) or (fbaA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 4.1.2.13 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fba) or (fbaA) PROTEIN_ASSOCIATION: SUBSYSTEM: Inositol_metabolism PROTEIN_CLASS: 4.1.2.13 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fbp) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 3.1.3.11 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hemH) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.99.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fdhF) PROTEIN_ASSOCIATION: SUBSYSTEM: Glyoxylate_and_dicarboxylate_metabolism PROTEIN_CLASS: 1.2.1.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (yfeA and yfeB and yfeC) or (yfeA and yfeB and yfeD) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ribF) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.7.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fmt) PROTEIN_ASSOCIATION: SUBSYSTEM: Folate_Metabolism PROTEIN_CLASS: 2.1.2.9 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (folA) PROTEIN_ASSOCIATION: SUBSYSTEM: Folate_Metabolism PROTEIN_CLASS: 1.5.1.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (folA) PROTEIN_ASSOCIATION: SUBSYSTEM: Folate_Metabolism PROTEIN_CLASS: 1.5.1.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (folA) PROTEIN_ASSOCIATION: SUBSYSTEM: Folate_Metabolism PROTEIN_CLASS: 1.5.1.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (folA) PROTEIN_ASSOCIATION: SUBSYSTEM: Folate_Metabolism PROTEIN_CLASS: 1.5.1.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (folC) PROTEIN_ASSOCIATION: SUBSYSTEM: Folate_Metabolism PROTEIN_CLASS: 6.3.2.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (folP) PROTEIN_ASSOCIATION: SUBSYSTEM: Folate_Metabolism PROTEIN_CLASS: 2.5.1.15 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (focA) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (frdA and frdB and frdC and frdD) PROTEIN_ASSOCIATION: SUBSYSTEM: Citrate_Cycle_(TCA) PROTEIN_CLASS: 1.3.99.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (frdA and frdB and frdC and frdD) PROTEIN_ASSOCIATION: SUBSYSTEM: Citrate_Cycle_(TCA) PROTEIN_CLASS: 1.3.99.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fruK) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.56 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fruA and fruB and ptsA) or (fruA and fruB and ptsI) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: 2.7.3.9 and EC-2.7.1.69 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fruA and fruB and ptsA) or (fruA and fruB and ptsI) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: 2.7.3.9 and EC-2.7.1.69 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (purU) PROTEIN_ASSOCIATION: SUBSYSTEM: Folate_Metabolism PROTEIN_CLASS: 3.5.1.10 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ftsI and mrcB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.4.1.129 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fumA) or (fumC) PROTEIN_ASSOCIATION: SUBSYSTEM: Citrate_Cycle_(TCA) PROTEIN_CLASS: 4.2.1.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dctA) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dcuA) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glmU) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.3.1.157 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (rffH) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.7.7.24 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hemL) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 5.4.3.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gpsA) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.94 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glpA and glpB and glpC) or (glpD and glpB and glpC) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.1.99.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glpA and glpB and glpC) or (glpD and glpB and glpC) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.1.99.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glpA and glpB and glpC) or (glpD and glpB and glpC) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.1.99.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: Non-enzymatic LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (proA) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.2.1.41 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nagB) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.5.99.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (zwf) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_Phosphate_Cycle PROTEIN_CLASS: 1.1.1.49 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (galK) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3545) or (malZ) or (galA) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.2.1.22, 3.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (galF) or (galU1) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.7.9 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (exuT1) or (exuT2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mglA4 and mglB and mglC) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 1.2.1.12 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (purN) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.1.2.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (purT) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.1.2.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gcvT) PROTEIN_ASSOCIATION: SUBSYSTEM: Folate_Metabolism PROTEIN_CLASS: 2.1.2.10 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (wcaG2) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glmS) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.6.1.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gmk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gntT1) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glgA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 2.4.1.21 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (exuT1) or (exuT2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (crr and ptsG and ptsH and ptsI) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: 2.7.3.9 and EC-2.7.1.69 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glgC) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 2.7.7.27 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glk) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 2.7.1.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glnA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glutamate_metabolism PROTEIN_CLASS: 6.3.1.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glnH and glnP and glnQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (proB) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.7.2.11 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gshA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 6.3.2.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (adiA) or (speA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glutamate_metabolism PROTEIN_CLASS: 4.1.1.19 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gdhA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glutamate_metabolism PROTEIN_CLASS: 1.4.1.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glsA1) or (glsA2) PROTEIN_ASSOCIATION: SUBSYSTEM: Glutamate_metabolism PROTEIN_CLASS: 3.5.1.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (purF) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.4.2.14 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (murI) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 5.1.1.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gltB) PROTEIN_ASSOCIATION: SUBSYSTEM: Glutamate_metabolism PROTEIN_CLASS: 1.4.1.13 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hemA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.2.1.70 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gltX) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 6.1.1.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glnH1 and gltJ1 and gltK and gltL) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gltP) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gltS) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glpF) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (kbl) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycine_and_Serine_Metabolism PROTEIN_CLASS: 2.3.1.29 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (proV2 and proW3 and proX) PROTEIN_ASSOCIATION: SUBSYSTEM: Putative_Transporters PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (betT2) PROTEIN_ASSOCIATION: SUBSYSTEM: Putative_Transporters PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ugpA and ugpB5 and ugpC and ugpE) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glxK) PROTEIN_ASSOCIATION: SUBSYSTEM: Glyoxylate_Metabolism PROTEIN_CLASS: 2.7.1.31 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gcvT) PROTEIN_ASSOCIATION: SUBSYSTEM: Folate_Metabolism PROTEIN_CLASS: 2.1.2.10 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ptsG) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glpF) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glpK1) or (glpK2) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.30 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gloB3) PROTEIN_ASSOCIATION: SUBSYSTEM: Methylglyoxal_Metabolism PROTEIN_CLASS: 3.1.2.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ansP3) or (cycA) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (rfaE) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (rfaE) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hisB2) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (guaC) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 1.7.1.7 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (guaA) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 6.3.5.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gnd) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_Phosphate_Cycle PROTEIN_CLASS: 1.1.1.44 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gntV) or (idnK) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.12 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (goaG) PROTEIN_ASSOCIATION: SUBSYSTEM: Propanoate_metabolism PROTEIN_CLASS: 2.6.1.19 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (goaG) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_Leucine_isoleucine_metabolism PROTEIN_CLASS: 2.6.1.22 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (wcaG2) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (apaH) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.6.1.41 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glpQ) or (ugpQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.4.46 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glpQ) or (ugpQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.4.46 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glpQ) or (ugpQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.4.46 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glpQ) or (ugpQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.4.46 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glpQ) or (ugpQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.4.46 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gpsA) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.94 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ispA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.5.1.10 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gsk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.1.73 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gor) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.8.1.7 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gshB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 6.3.2.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (folE) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 3.5.4.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ribA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 3.5.4.25 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (apt1 and gpt and hpt) or (apt2 and gpt and hpt) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.4.2.7 2.4.2.8 2.4.2.22 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (uxaC) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.3.1.12 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (uxaC) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.3.1.12 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gutB) PROTEIN_ASSOCIATION: SUBSYSTEM: Fructose_and_mannose_metabolism PROTEIN_CLASS: 1.1.1.14 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ubiA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.5.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cynT1) or (cynT2) PROTEIN_ASSOCIATION: SUBSYSTEM: Unassigned PROTEIN_CLASS: 4.2.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fadL) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cyoE) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hemN1) or (hemN2) PROTEIN_ASSOCIATION: SUBSYSTEM: Porphyrin_metabolism PROTEIN_CLASS: 1.3.99.22 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hisD) PROTEIN_ASSOCIATION: SUBSYSTEM: Histidine_Metabolism PROTEIN_CLASS: 1.1.1.23 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hisB1) PROTEIN_ASSOCIATION: SUBSYSTEM: Histidine_Metabolism PROTEIN_CLASS: 3.1.3.15 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hisJ and hisM and hisP and hisQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ansP3) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hemC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.5.1.61 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (thiD) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.49 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hpaB) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_metabolism PROTEIN_CLASS: 1.14.13.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hpaB) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_metabolism PROTEIN_CLASS: 1.14.13.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hpaD) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_metabolism PROTEIN_CLASS: 1.13.11.15 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hpaF) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_metabolism PROTEIN_CLASS: 5.3.3.10 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hpaH) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_metabolism PROTEIN_CLASS: 4.2.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hpaH) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_metabolism PROTEIN_CLASS: 4.2.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hpaI) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_metabolism PROTEIN_CLASS: 4.1.2.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (folK) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.6.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hfi1) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.3.1.22 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ldhA2) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.81 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ldhA2) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.81 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (metL) or (thrA) PROTEIN_ASSOCIATION: SUBSYSTEM: Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 1.1.1.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (thrB) PROTEIN_ASSOCIATION: SUBSYSTEM: Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 2.7.1.39 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (metA) PROTEIN_ASSOCIATION: SUBSYSTEM: Methionine_Metabolism PROTEIN_CLASS: 2.3.1.46 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hisC) PROTEIN_ASSOCIATION: SUBSYSTEM: Histidine_Metabolism PROTEIN_CLASS: 2.6.1.9 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hutG) PROTEIN_ASSOCIATION: SUBSYSTEM: Histidine_Metabolism PROTEIN_CLASS: 3.5.3.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hutH) PROTEIN_ASSOCIATION: SUBSYSTEM: Nitrogen_Metabolism PROTEIN_CLASS: .4.3.1.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hutI) PROTEIN_ASSOCIATION: SUBSYSTEM: Histidine_Metabolism PROTEIN_CLASS: 3.5.2.7 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hutU) PROTEIN_ASSOCIATION: SUBSYSTEM: Histidine_Metabolism PROTEIN_CLASS: 4.2.1.49 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hpt) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.4.2.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (icdA) PROTEIN_ASSOCIATION: SUBSYSTEM: Citrate_Cycle_(TCA) PROTEIN_CLASS: 1.1.1.42 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (menF) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 5.4.4.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aceA) PROTEIN_ASSOCIATION: SUBSYSTEM: Anaplerotic_reactions PROTEIN_CLASS: 4.1.3.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hisF and hisH) PROTEIN_ASSOCIATION: SUBSYSTEM: Histidine_Metabolism PROTEIN_CLASS: 2.4.2.- and EC-4.1.3.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hisB1) PROTEIN_ASSOCIATION: SUBSYSTEM: Histidine_Metabolism PROTEIN_CLASS: 4.2.1.19 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (trpC) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_Tryptophan_and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.1.1.48 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ilvE) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_leucine_and_isoleucine_metabolism PROTEIN_CLASS: 2.6.1.42 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (livF and livG and livH and livK2 and livM and livK1 and livM2 and livG1 and livF1) or (livF and livG and livH and livK2 and livM1 and livK1 and livM2 and livG1 and livF1) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (brnQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (purH) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 3.5.4.10 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (guaB) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 1.1.1.205 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mtr) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gsk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.1.73 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ispH) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.17.1.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (leuB2) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_leucine_and_isoleucine_metabolism PROTEIN_CLASS: 1.1.1.85 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (leuC and leuD) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_leucine_and_isoleucine_metabolism PROTEIN_CLASS: 4.2.1.33 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (leuC and leuD) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_leucine_and_isoleucine_metabolism PROTEIN_CLASS: 4.2.1.33 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (leuA) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_leucine_and_isoleucine_metabolism PROTEIN_CLASS: 2.3.3.13 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (iucB) PROTEIN_ASSOCIATION: SUBSYSTEM: Lysine_degradation PROTEIN_CLASS: 2.3.1.102 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (iucC) PROTEIN_ASSOCIATION: SUBSYSTEM: Lysine_degradation PROTEIN_CLASS: 6.3.2.27 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (iucD) PROTEIN_ASSOCIATION: SUBSYSTEM: Lysine_degradation PROTEIN_CLASS: 1.14.13.59 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ilvC) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_leucine_and_isoleucine_metabolism PROTEIN_CLASS: 1.1.1.86 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ilvC) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_leucine_and_isoleucine_metabolism PROTEIN_CLASS: 1.1.1.86 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fabB) or (fabF3) or (fabF4) or (fabH2) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: 2.3.1.41 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fabH2) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: 2.3.1.41 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fabB and fabG) or (fabB and fabG6) or (fabF3 and fabG) or (fabF3 and fabG6) or (fabF4 and fabG) or (fabF4 and fabG6) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: 1.1.1.100, EC-2.3.1.41 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (katA) or (katG) PROTEIN_ASSOCIATION: SUBSYSTEM: Tryptophan_Metabolism PROTEIN_CLASS: 1.11.1.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (katA) or (katG) PROTEIN_ASSOCIATION: SUBSYSTEM: Methane_metabolism PROTEIN_CLASS: 1.11.1.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (kdsB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.7.7.38 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3833) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.3.45 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (kdsA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.5.1.55 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (kdtX and rfaC and rfaF and rfaQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (kduD) or (kduD2) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_and_Glucoronate_Interconverstion PROTEIN_CLASS: 1.1.1.125 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (kduI) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_and_Glucoronate_Interconverstion PROTEIN_CLASS: 5.3.1.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (kdpA and kdpB and kdpC and kdpD1 and kdpE) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: 3.6.3.12 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (trkH) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (lldD) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.1.2.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (lldD) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.1.2.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ptsG) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (bgaB) or (lacZ) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycerolipid_Metabolism PROTEIN_CLASS: 3.2.1.23 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.2.1.22 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dld) PROTEIN_ASSOCIATION: SUBSYSTEM: Pyruvate_metabolism PROTEIN_CLASS: 1.1.1.28 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ilvE) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_leucine_and_isoleucine_metabolism PROTEIN_CLASS: 2.6.1.42 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (livF and livG and livH and livK2 and livM and livK1 and livM2 and livG1 and livF1) or (livF and livG and livH and livK2 and livM1 and livK1 and livM2 and livG1 and livF1) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (brnQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gloA1) PROTEIN_ASSOCIATION: SUBSYSTEM: Methylglyoxal_Metabolism PROTEIN_CLASS: 4.4.1.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_and_Glucoronate_Interconverstion PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.1.3.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Starch_and_sucrose_metabolism PROTEIN_CLASS: 1.17.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (lpxB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.4.1.182 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ltaA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycine_metabolism PROTEIN_CLASS: 4.1.2.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (luxS) PROTEIN_ASSOCIATION: SUBSYSTEM: Methionine_Metabolism PROTEIN_CLASS: 4.4.1.21 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (lysP) or (ansP3) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mtlD2) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fabB) or (fabF3) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: 2.3.1.41 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aceB) PROTEIN_ASSOCIATION: SUBSYSTEM: Anaplerotic_reactions PROTEIN_CLASS: 2.3.3.9 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3554 and malE2 and malF7 and malG7 and malF and malG and malK2) or (YP3554 and malE2 and malF7 and malE and malF and malG and malK2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3554 and malE2 and malF7 and malG7 and malF and malG and malK2) or (YP3554 and malE2 and malF7 and malE and malF and malG and malK2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3554 and malE2 and malF7 and malG7 and malF and malG and malK2) or (YP3554 and malE2 and malF7 and malE and malF and malG and malK2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3554 and malE2 and malF7 and malG7 and malF and malG and malK2) or (YP3554 and malE2 and malF7 and malE and malF and malG and malK2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3554 and malE2 and malF7 and malG7 and malF and malG and malK2) or (YP3554 and malE2 and malF7 and malE and malF and malG and malK2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dctA) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dcuA) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (manA) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.3.1.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mtlD1) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.57 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (manX1 and manY and manZ and ptsH and ptsI) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: 2.7.3.9 and EC-2.7.1.69 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fabD1) or (fabD2) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: 2.3.1.39 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mdh) PROTEIN_ASSOCIATION: SUBSYSTEM: Citrate_Cycle_(TCA) PROTEIN_CLASS: 1.1.1.37 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (sfcA1) PROTEIN_ASSOCIATION: SUBSYSTEM: Anaplerotic_reactions PROTEIN_CLASS: 1.1.1.38 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (sfcA2) PROTEIN_ASSOCIATION: SUBSYSTEM: Anaplerotic_reactions PROTEIN_CLASS: 1.1.1.40 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ispG) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.17.4.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ispF) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.6.1.12 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (melB) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (menA) PROTEIN_ASSOCIATION: SUBSYSTEM: Ubiquinone_biosynthesis PROTEIN_CLASS: 2.5.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (menB) PROTEIN_ASSOCIATION: SUBSYSTEM: Ubiquinone_biosynthesis PROTEIN_CLASS: 4.1.3.36 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ispD) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.7.60 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (metK) PROTEIN_ASSOCIATION: SUBSYSTEM: Methionine_Metabolism PROTEIN_CLASS: 2.5.1.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (metC1) PROTEIN_ASSOCIATION: SUBSYSTEM: Methionine_Metabolism PROTEIN_CLASS: 2.5.1.48 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (metC1) PROTEIN_ASSOCIATION: SUBSYSTEM: Methionine_Metabolism PROTEIN_CLASS: 2.5.1.48 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (metC1) PROTEIN_ASSOCIATION: SUBSYSTEM: Methionine_Metabolism PROTEIN_CLASS: 2.5.1.48 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (metC1) PROTEIN_ASSOCIATION: SUBSYSTEM: Methionine_Metabolism PROTEIN_CLASS: 2.5.1.48 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (metC1) PROTEIN_ASSOCIATION: SUBSYSTEM: Selenoamino_acid_metabolism PROTEIN_CLASS: 2.5.1.48 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2777 and metN and metQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (metE) PROTEIN_ASSOCIATION: SUBSYSTEM: Methionine_Metabolism PROTEIN_CLASS: 2.1.1.14 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (metK) PROTEIN_ASSOCIATION: SUBSYSTEM: Selenoamino_acid_metabolism PROTEIN_CLASS: 2.5.1.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (metH) PROTEIN_ASSOCIATION: SUBSYSTEM: Methionine_Metabolism PROTEIN_CLASS: 2.1.1.13 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2777 and metN and metQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mgsA) PROTEIN_ASSOCIATION: SUBSYSTEM: Methylglyoxal_Metabolism PROTEIN_CLASS: 4.2.3.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (suhB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.3.25 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3545) or (malZ) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3545) or (malZ) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3545) or (malZ) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3545) or (malZ) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3545) or (malZ) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glgP) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.4.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glgP) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.4.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glgP) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.4.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.1.99.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.4.99.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mtlA and ptsH and ptsI) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: 2.7.3.9 and EC-2.7.1.69 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (uxuA) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.2.1.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (kdtA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (kdtA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (panB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.1.2.11 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mtn) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 3.2.2.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (folD) PROTEIN_ASSOCIATION: SUBSYSTEM: Folate_Metabolism PROTEIN_CLASS: 3.5.4.9 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (folD) PROTEIN_ASSOCIATION: SUBSYSTEM: Folate_Metabolism PROTEIN_CLASS: 1.5.1.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (metF) or (metF2) PROTEIN_ASSOCIATION: SUBSYSTEM: Folate_Metabolism PROTEIN_CLASS: 1.5.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (argE2) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 3.5.1.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nadB) PROTEIN_ASSOCIATION: SUBSYSTEM: alanine_and_aspartate_metabolism PROTEIN_CLASS: 1.4.3.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nadE) PROTEIN_ASSOCIATION: SUBSYSTEM: Nicotinate_and_nicotinamide_metabolism PROTEIN_CLASS: 6.3.5.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ndh and nuoA and nuoB and nuoD and nuoE and nuoF and nuoG and nuoH and nuoI and nuoJ and nuoK and nuoL and nuoM and nuoN) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.6.5.3 and EC.1.6.99.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ndh and nuoA and nuoB and nuoD and nuoE and nuoF and nuoG and nuoH and nuoI and nuoJ and nuoK and nuoL and nuoM and nuoN) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.6.5.3 and EC.1.6.99.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ndh and nuoA and nuoB and nuoD and nuoE and nuoF and nuoG and nuoH and nuoI and nuoJ and nuoK and nuoL and nuoM and nuoN) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.6.5.3 and EC.1.6.99.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ndh and nuoA and nuoB and nuoD and nuoE and nuoF and nuoG and nuoH and nuoI and nuoJ and nuoK and nuoL and nuoM and nuoN) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.6.5.3 and EC.1.6.99.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ndh and nuoA and nuoB and nuoD and nuoE and nuoF and nuoG and nuoH and nuoI and nuoJ and nuoK and nuoL and nuoM and nuoN) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.6.5.3 and EC.1.6.99.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ndh and nuoA and nuoB and nuoD and nuoE and nuoF and nuoG and nuoH and nuoI and nuoJ and nuoK and nuoL and nuoM and nuoN) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.6.5.3 and EC.1.6.99.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ppnK) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.23 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (chaA) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nhaB) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nhaA) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ndk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ndk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ndk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ndk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ndk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ndk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ndk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ndk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ndk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ndk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: Galactose_metabolism PROTEIN_CLASS: non-enzymatic LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: Glyoxylate_and_dicarboxylate_metabolism PROTEIN_CLASS: non-enzymatic LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: Glyoxylate_and_dicarboxylate_metabolism PROTEIN_CLASS: non-enzymatic LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_phosphate_pathway PROTEIN_CLASS: non-enzymatic LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: Flourene_degradation PROTEIN_CLASS: non-enzymatic LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: non-enzymatic LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_metabolism PROTEIN_CLASS: non-enzymatic LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_metabolism PROTEIN_CLASS: non-enzymatic LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: Selenoamino_acid_metabolism PROTEIN_CLASS: non-enzymatic LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: Selenoamino_acid_metabolism PROTEIN_CLASS: non-enzymatic LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: Thiamine_metabolism PROTEIN_CLASS: non-enzymatic LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nadD) or (nadR) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.7.1 or EC-2.7.7.18 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 3.5.1.42 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pnuC) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pncA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 3.5.1.19 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nadD) or (nadR) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.7.1 or EC-2.7.7.18 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nadC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.4.2.19 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nirC) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (napA) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.7.99.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (napA) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.7.99.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2370) or (surE) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.1.3.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2370) or (surE) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.1.3.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2370) or (surE) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.1.3.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2370) or (surE) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.1.3.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2370) or (surE) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.1.3.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2370) or (surE) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.1.3.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2370) or (surE) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.1.3.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2370) or (surE) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.1.3.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2370) or (surE) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.1.3.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2370) or (surE) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.1.3.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2370) or (surE) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.1.3.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mazG) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mazG) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mazG) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mazG) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mazG) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mazG) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mazG) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mazG) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dgt) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.1.5.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dgt) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 3.1.5.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nirB and nirD) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.7.1.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nuoA and nuoB and nuoD and nuoE and nuoF and nuoG and nuoH and nuoI and nuoJ and nuoK and nuoL and nuoM and nuoN) PROTEIN_ASSOCIATION: SUBSYSTEM: Ubiquinone_biosynthesis PROTEIN_CLASS: 1.6.5.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pflB) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.3.1.54 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (argI) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.1.3.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fadL) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ispB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ogl) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_and_Glucoronate_Interconverstion PROTEIN_CLASS: 4.2.2.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (serC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.6.1.52 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ubiG) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.1.1.64 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ubiE) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.1.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (leuB2) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_leucine_and_isoleucine_metabolism PROTEIN_CLASS: 1.1.1.85 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ubiF) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.14.13.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pyrF) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 4.1.1.23 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ubiH) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ubiX) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.1.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ubiB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: UbiB LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (speC) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 4.1.1.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pyrE) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.4.2.10 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (putA) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.5.1.12 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (proC) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.5.1.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (panC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 6.3.2.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mraY) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.7.8.13 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aceE and aceF and lpd) or (aceE and aceF and lpdA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 1.2.4.1 1.8.1.4 2.3.1.12 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pdxH) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.4.3.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pdxA and pdxJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.1.1.262 and EC-2.6.99.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pdxH) PROTEIN_ASSOCIATION: SUBSYSTEM: Thiamine_metabolism PROTEIN_CLASS: 1.4.3.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pdxH) PROTEIN_ASSOCIATION: SUBSYSTEM: Thiamine_metabolism PROTEIN_CLASS: 1.4.3.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pepD1) PROTEIN_ASSOCIATION: SUBSYSTEM: alanine_and_aspartate_metabolism PROTEIN_CLASS: 3.4.13.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pepD1) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 3.4.13.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pepN) PROTEIN_ASSOCIATION: SUBSYSTEM: Glutathione_metabolism PROTEIN_CLASS: 3.4.11.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pepN) PROTEIN_ASSOCIATION: SUBSYSTEM: Glutathione_metabolism PROTEIN_CLASS: 3.4.11.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pepT) PROTEIN_ASSOCIATION: SUBSYSTEM: Glutathione_metabolism PROTEIN_CLASS: 3.4.11.4 and EC-2.3.2.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pdxB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.1.1.290 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pfkA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 2.7.1.11 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (agaZ) or (pfkA) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.11, 2.7.1.144 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pflB) PROTEIN_ASSOCIATION: SUBSYSTEM: Pyruvate_metabolism PROTEIN_CLASS: 2.3.1.54 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glmM) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 5.4.2.10 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (serA1) or (serA2) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycine_and_Serine_Metabolism PROTEIN_CLASS: 1.1.1.95 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pgi) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 5.3.1.9 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pgk) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 2.7.2.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP1011) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_Phosphate_Cycle PROTEIN_CLASS: 3.1.1.31 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gph) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.1.3.18 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gpmA) or (gpmB) or (gpmI) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 5.4.2.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pgm) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.4.2.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pgpA and pgpB5) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: 3.1.3.27 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pgsA2) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: 2.7.8.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pheA) PROTEIN_ASSOCIATION: SUBSYSTEM: Phenylalanine_Metabolism PROTEIN_CLASS: 4.2.1.51 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aspC) or (hisC) or (tyrB) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_Tryptophan_and_Phenylalanine_Metabolism PROTEIN_CLASS: 2.6.1.1 or EC-2.6.1.9 or EC-2.6.1.57 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aroP1) or (aroP2) or (aroP3) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (phoA) PROTEIN_ASSOCIATION: SUBSYSTEM: Folate_Metabolism PROTEIN_CLASS: 3.1.3.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (phoA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycerolipid_Metabolism PROTEIN_CLASS: 3.1.3.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pstA and pstB1 and pstC and pstS1) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pitA) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pldA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.1.32 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pldA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.1.32 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pldA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.1.32 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pldB2) or (tesA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.1.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pldB2) or (tesA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.1.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pldB2) or (tesA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.1.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pldB2) or (tesA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.1.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pldB2) or (tesA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.1.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (plsB) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycerolipid_Metabolism PROTEIN_CLASS: 2.3.1.15 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (plsC2) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycerolipid_Metabolism PROTEIN_CLASS: 2.3.1.51 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (manB1) or (manB2) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.4.2.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2373) or (aceK) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 3.1.3.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (thiD) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.4.7 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pmrF) PROTEIN_ASSOCIATION: SUBSYSTEM: Aminophosphonate_metabolism PROTEIN_CLASS: 2.7.8.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pncB) PROTEIN_ASSOCIATION: SUBSYSTEM: Nicotinate_and_nicotinamide_metabolism PROTEIN_CLASS: 2.4.2.11 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (coaA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.33 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (actP) or (panF) or (putP2) or (putP4) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (poxB) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.2.2.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ppa) PROTEIN_ASSOCIATION: SUBSYSTEM: Anaplerotic_reactions PROTEIN_CLASS: 3.6.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ackA) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.2.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hemB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.2.1.24 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ppc) PROTEIN_ASSOCIATION: SUBSYSTEM: Anaplerotic_reactions PROTEIN_CLASS: 4.1.1.31 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dfp) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.1.1.36 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pckA) PROTEIN_ASSOCIATION: SUBSYSTEM: Anaplerotic_reactions PROTEIN_CLASS: 4.1.1.49 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ppk) PROTEIN_ASSOCIATION: SUBSYSTEM: oxidative_phosphorylation PROTEIN_CLASS: 2.7.4.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (deoB) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.4.2.7 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (deoB) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.4.2.7 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dfp) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 6.3.2.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pheA) or (pheA2) or (tyrA) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_Tryptophan_and_Phenylalanine_Metabolism PROTEIN_CLASS: 1.3.1.12 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pheA) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_Tryptophan_and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.2.1.51 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hemG) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.3.3.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ppsA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 2.7.9.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gppA) or (ppx) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_metabolism PROTEIN_CLASS: 3.6.1.11 or EC-3.6.1.40 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (purD) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 6.3.4.13 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (purI) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 6.3.3.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (trpC) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_Tryptophan_and_Phenylalanine_Metabolism PROTEIN_CLASS: 5.3.1.24 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hisI) PROTEIN_ASSOCIATION: SUBSYSTEM: Histidine_Metabolism PROTEIN_CLASS: 3.5.4.19 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (purC) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 6.3.2.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hisI) PROTEIN_ASSOCIATION: SUBSYSTEM: Histidine_Metabolism PROTEIN_CLASS: 3.6.1.31 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (purL) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 6.3.5.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (prk) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_and_Glucoronate_Interconverstion PROTEIN_CLASS: 2.7.1.19 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hisA) PROTEIN_ASSOCIATION: SUBSYSTEM: Histidine_Metabolism PROTEIN_CLASS: 5.3.1.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (proC) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.5.1.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (proC) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.5.1.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (putA) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.5.99.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (proV2 and proW3 and proX) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (actP) or (panF) or (putP2) or (putP4) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (prsA) PROTEIN_ASSOCIATION: SUBSYSTEM: Histidine_Metabolism PROTEIN_CLASS: 2.7.6.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aroA) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_Tryptophan_and_Phenylalanine_Metabolism PROTEIN_CLASS: 2.5.1.19 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (psd) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: 4.1.1.65 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (serC) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycine_and_Serine_Metabolism PROTEIN_CLASS: 2.6.1.52 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (serB) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycine_and_Serine_Metabolism PROTEIN_CLASS: 3.1.3.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pssA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycerophospholipid_metabolism PROTEIN_CLASS: 2.7.8.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pta) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.3.1.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pta) PROTEIN_ASSOCIATION: SUBSYSTEM: Pyruvate_metabolism PROTEIN_CLASS: 2.3.1.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (coaD) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.7.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2713 and potB2 and potC2 and potD and potI and potH and potG) or (YP2713 and potB2 and potC2 and potF and potI and potH and potG) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (deoD) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.4.2.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (deoD) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.4.2.1, 2.4.2.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (deoD) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.4.2.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (deoD) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.4.2.1, 2.4.2.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (deoD) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.4.2.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (deoD) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.4.2.1, 2.4.2.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (deoD) or (xapA) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.4.2.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (purN) PROTEIN_ASSOCIATION: SUBSYSTEM: Folate_Metabolism PROTEIN_CLASS: 2.1.2.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (putA) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.5.1.12 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (putA) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.5.1.12 or EC-1.5.99.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (putA) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: .1.5.1.12 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (putA) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.5.1.12 or EC-1.5.99.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pdxH) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.4.3.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pdxY) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.35 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pdxY) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.35 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pdxY) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.35 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pykA) or (pykF) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 2.7.1.40 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pykA) or (pykF) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 2.7.1.40 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pykA) or (pykF) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 2.7.1.40 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pykA) or (pykF) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 2.7.1.40 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pykA) or (pykF) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 2.7.1.40 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pykA) or (pykF) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 2.7.1.40 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pykA) or (pykF) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 2.7.1.40 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (udp) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.4.2.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gapfilled) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nadA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: NadA LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (galA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycerolipid_Metabolism PROTEIN_CLASS: 3.2.1.22 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (galA) PROTEIN_ASSOCIATION: SUBSYSTEM: Galactose_metabolism PROTEIN_CLASS: 3.2.1.22 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (galA) PROTEIN_ASSOCIATION: SUBSYSTEM: Galactose_metabolism PROTEIN_CLASS: 3.2.1.22 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (galA) PROTEIN_ASSOCIATION: SUBSYSTEM: Galactose_metabolism PROTEIN_CLASS: 3.2.1.22 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (galA) PROTEIN_ASSOCIATION: SUBSYSTEM: Galactose_metabolism PROTEIN_CLASS: 3.2.1.22 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (galA) PROTEIN_ASSOCIATION: SUBSYSTEM: Galactose_metabolism PROTEIN_CLASS: 3.2.1.22 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (galA) PROTEIN_ASSOCIATION: SUBSYSTEM: Galactose_metabolism PROTEIN_CLASS: 3.2.1.22 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (galA) PROTEIN_ASSOCIATION: SUBSYSTEM: Sphingolipid_metabolism PROTEIN_CLASS: 3.2.1.22 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ribF) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.26 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ribH) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: RIBH LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ribE) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.5.1.9 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (rbsK1) or (rbsK5) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.15 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (araB1) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP0360) or (YP2029) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.1.3.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (relA) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_metabolism PROTEIN_CLASS: 2.7.6.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (kdtX and rfaC and rfaF and rfaQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (kdtX and rfaC and rfaF and rfaQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (rffE) PROTEIN_ASSOCIATION: SUBSYSTEM: Aminosugars_metabolism PROTEIN_CLASS: 5.1.3.14 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (rhaB) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_and_Glucoronate_Interconverstion PROTEIN_CLASS: 2.7.1.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (rhaD) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_and_Glucoronate_Interconverstion PROTEIN_CLASS: 4.1.2.19 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (rbsD1 and YP1133 and YP1134 and YP1132 and YP2315 and YP2316 and YP2314 and YP3327 and YP3325 and YP3326 and YP3482 and YP3484 and YP3483 and YP3557 and YP3556 and YP3555) or (rbsD1 and YP1133 and YP1134 and YP1132 and YP2315 and YP2316 and YP2314 and YP3327 and YP3325 and YP3326 and YP3482 and YP3484 and rbsD1 and YP3557 and YP3556 and YP3555) or (rbsD1 and YP1133 and YP1134 and YP1132 and YP2315 and YP2316 and YP2314 and YP3327 and YP3325 and rbsD1 and YP3482 and YP3484 and YP3483 and YP3557 and YP3556 and YP3555) or (rbsD1 and YP1133 and YP1134 and YP1132 and YP2315 and YP2316 and YP2314 and YP3327 and YP3325 and rbsD1 and YP3482 and YP3484 and rbsD1 and YP3557 and YP3556 and YP3555) or (rbsD1 and YP1133 and YP1134 and YP1132 and YP2315 and YP2316 and rbsD1 and YP3327 and YP3325 and YP3326 and YP3482 and YP3484 and YP3483 and YP3557 and YP3556 and YP3555) or (rbsD1 and YP1133 and YP1134 and YP1132 and YP2315 and YP2316 and rbsD1 and YP3327 and YP3325 and YP3326 and YP3482 and YP3484 and rbsD1 and YP3557 and YP3556 and YP3555) or (rbsD1 and YP1133 and YP1134 and YP1132 and YP2315 and YP2316 and rbsD1 and YP3327 and YP3325 and rbsD1 and YP3482 and YP3484 and YP3483 and YP3557 and YP3556 and YP3555) or (rbsD1 and YP1133 and YP1134 and YP1132 and YP2315 and YP2316 and rbsD1 and YP3327 and YP3325 and rbsD1 and YP3482 and YP3484 and rbsD1 and YP3557 and YP3556 and YP3555) or (rbsD1 and YP1133 and YP1134 and rbsD1 and YP2315 and YP2316 and YP2314 and YP3327 and YP3325 and YP3326 and YP3482 and YP3484 and YP3483 and YP3557 and YP3556 and YP3555) or (rbsD1 and YP1133 and YP1134 and rbsD1 and YP2315 and YP2316 and YP2314 and YP3327 and YP3325 and YP3326 and YP3482 and YP3484 and rbsD1 and YP3557 and YP3556 and YP3555) or (rbsD1 and YP1133 and YP1134 and rbsD1 and YP2315 and YP2316 and YP2314 and YP3327 and YP3325 and rbsD1 and YP3482 and YP3484 and YP3483 and YP3557 and YP3556 and YP3555) or (rbsD1 and YP1133 and YP1134 and rbsD1 and YP2315 and YP2316 and YP2314 and YP3327 and YP3325 and rbsD1 and YP3482 and YP3484 and rbsD1 and YP3557 and YP3556 and YP3555) or (rbsD1 and YP1133 and YP1134 and rbsD1 and YP2315 and YP2316 and rbsD1 and YP3327 and YP3325 and YP3326 and YP3482 and YP3484 and YP3483 and YP3557 and YP3556 and YP3555) or (rbsD1 and YP1133 and YP1134 and rbsD1 and YP2315 and YP2316 and rbsD1 and YP3327 and YP3325 and YP3326 and YP3482 and YP3484 and rbsD1 and YP3557 and YP3556 and YP3555) or (rbsD1 and YP1133 and YP1134 and rbsD1 and YP2315 and YP2316 and rbsD1 and YP3327 and YP3325 and rbsD1 and YP3482 and YP3484 and YP3483 and YP3557 and YP3556 and YP3555) or (rbsD1 and YP1133 and YP1134 and rbsD1 and YP2315 and YP2316 and rbsD1 and YP3327 and YP3325 and rbsD1 and YP3482 and YP3484 and rbsD1 and YP3557 and YP3556 and YP3555) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (rhaA) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.3.1.14 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (rhaB) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (rhaT2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (rhaD) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.1.2.19 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP0924 and YPpMT047) or (YP0924 and nrdA) or (YP0924 and nrdE) or (YPpMT046 and YPpMT047) or (YPpMT046 and nrdA) or (YPpMT046 and nrdE) or (nrdF and YPpMT047) or (nrdF and nrdA) or (nrdF and nrdE) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 1.17.4.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP0924 and YPpMT047) or (YP0924 and nrdA) or (YP0924 and nrdE) or (YPpMT046 and YPpMT047) or (YPpMT046 and nrdA) or (YPpMT046 and nrdE) or (nrdF and YPpMT047) or (nrdF and nrdA) or (nrdF and nrdE) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 1.17.4.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP0924 and YPpMT047) or (YP0924 and nrdA) or (YP0924 and nrdE) or (YPpMT046 and YPpMT047) or (YPpMT046 and nrdA) or (YPpMT046 and nrdE) or (nrdF and YPpMT047) or (nrdF and nrdA) or (nrdF and nrdE) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 1.17.4.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP0924 and YPpMT047) or (YP0924 and nrdA) or (YP0924 and nrdE) or (YPpMT046 and YPpMT047) or (YPpMT046 and nrdA) or (YPpMT046 and nrdE) or (nrdF and YPpMT047) or (nrdF and nrdA) or (nrdF and nrdE) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 1.17.4.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nrdD) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 1.17.4.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nrdD) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 1.17.4.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nrdD) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 1.17.4.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nrdD) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 1.17.4.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (rpe) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_Phosphate_Cycle PROTEIN_CLASS: 5.1.3.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (rpiA1) or (rpiA2) or (rpiB1) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_Phosphate_Cycle PROTEIN_CLASS: 5.3.1.6 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2373) or (aceK) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 3.1.3.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP0689) or (YP3804) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (astB) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 3.5.3.23 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cysN) PROTEIN_ASSOCIATION: SUBSYSTEM: Cysteine_Metabolism PROTEIN_CLASS: 2.7.7.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (sdaA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cysteine_Metabolism PROTEIN_CLASS: 4.3.1.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (sdaA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cysteine_Metabolism PROTEIN_CLASS: 2.5.1.47 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (sdaA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cysteine_Metabolism PROTEIN_CLASS: 2.5.1.47 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dapE) PROTEIN_ASSOCIATION: SUBSYSTEM: Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 3.5.1.18 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP0172) PROTEIN_ASSOCIATION: SUBSYSTEM: Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 2.6.1.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (selD) PROTEIN_ASSOCIATION: SUBSYSTEM: Unassigned PROTEIN_CLASS: 2.7.9.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cysE) PROTEIN_ASSOCIATION: SUBSYSTEM: Cysteine_Metabolism PROTEIN_CLASS: 2.3.1.30 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ilvA and sdaA) or (tdcB and sdaA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycine_and_Serine_Metabolism PROTEIN_CLASS: 4.3.1.17 EC-4.3.1.19 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ansP3) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (sdaC2) or (sstT) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (sgbK) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_and_Glucoronate_Interconverstion PROTEIN_CLASS: 2.7.1.53 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP1711) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 3.5.1.96 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (astD) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.2.1.71 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (menD) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.5.1.64 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP0245) or (YP2244) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_Tryptophan_and_Phenylalanine_Metabolism PROTEIN_CLASS: 1.1.1.25 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aroK) or (aroL) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_Tryptophan_and_Phenylalanine_Metabolism PROTEIN_CLASS: 2.7.1.71 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (metC1) PROTEIN_ASSOCIATION: SUBSYSTEM: Methionine_Metabolism PROTEIN_CLASS: 2.5.1.48 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (solA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycine_metabolism PROTEIN_CLASS: 1.5.3.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP1707) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.6.1.81 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (speE) PROTEIN_ASSOCIATION: SUBSYSTEM: b-alanine_metabolism PROTEIN_CLASS: 2.5.1.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (speG) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.3.1.57 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (speG) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.3.1.57 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (speG) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.3.1.57 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2713 and potB2 and potC2 and potD) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (speE) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.5.1.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (sodA) or (sodB) or (sodC) PROTEIN_ASSOCIATION: SUBSYSTEM: Unassigned PROTEIN_CLASS: 1.15.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (spoT) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_metabolism PROTEIN_CLASS: 3.1.7.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gabD1) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.2.1.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gabD1) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.2.1.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (tauB and tauA and tauC1 and tauC2 and tauA2) or (tauB and tauA and tauB2 and tauC2 and tauA2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (kgd and lpd and sucB) or (kgd and lpdA and sucB) PROTEIN_ASSOCIATION: SUBSYSTEM: Lysine_degradation PROTEIN_CLASS: 1.2.4.2 and 2.3.1.61 and 1.8.1.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (caiC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 6.2.1.26 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (menC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.2.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3828 and YP3829 and YP3830) PROTEIN_ASSOCIATION: SUBSYSTEM: Putative_Transporters PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dctA) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dcuA) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dcuA) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (sucC) PROTEIN_ASSOCIATION: SUBSYSTEM: C5-branched_dibasic_acid_metabolsim PROTEIN_CLASS: 6.2.1.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (sdhA and sdhB and sdhC and sdhD) PROTEIN_ASSOCIATION: SUBSYSTEM: Citrate_Cycle_(TCA) PROTEIN_CLASS: 1.3.99.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (sdhA and sdhB and sdhC and sdhD) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: Undetermined LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dcuA) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (sucC and sucD) PROTEIN_ASSOCIATION: SUBSYSTEM: Citrate_Cycle_(TCA) PROTEIN_CLASS: 6.2.1.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (suhB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.3.25 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (suhB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.3.25 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cysI and cysJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Cysteine_Metabolism PROTEIN_CLASS: 1.8.1.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cysA and cysP and cysT and cysW) or (cysA and sbp and cysT and cysW) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (uxaB) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.58 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (talB) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_Phosphate_Cycle PROTEIN_CLASS: 2.2.1.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (tauD) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.14.11.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP0181 and YP0183 and YP0182 and YP2072 and YP2073) or (YP0181 and YP0183 and YP2071 and YP2072 and YP2073) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (rffC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (rffG) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 4.2.1.46 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (lpxK) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.7.1.130 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (kgd and lpd and sucB) or (kgd and lpdA and sucB) PROTEIN_ASSOCIATION: SUBSYSTEM: Citrate_Cycle_(TCA) PROTEIN_CLASS: 1.2.4.2 and 2.3.1.61 and 1.8.1.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pntA and pntB) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.6.1.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gatY) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.1.2.40 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (sthA) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.6.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dapD) PROTEIN_ASSOCIATION: SUBSYSTEM: Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 2.3.1.117 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nupC1) or (nupC2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (tbpA and thiP and thiQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ltaA) PROTEIN_ASSOCIATION: SUBSYSTEM: Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 4.1.2.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (tdh) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycine_and_Serine_Metabolism PROTEIN_CLASS: 1.1.1.103 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ilvA) or (tdcB) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_leucine_and_isoleucine_metabolism PROTEIN_CLASS: 4.3.1.19 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (thrC) PROTEIN_ASSOCIATION: SUBSYSTEM: Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 4.2.3.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (livF and livG and livH and livK2 and livM and livK1 and livM2 and livG1 and livF1) or (livF and livG and livH and livK2 and livM1 and livK1 and livM2 and livG1 and livF1) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ansP3) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (sstT) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (csdB1 and thiF and thiG and thiH and thiI) or (nifS and thiF and thiG and thiH and thiI) or (nifS2 and thiF and thiG and thiH and thiI) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (tktA1) or (tktA2) or (tktA3) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_Phosphate_Cycle PROTEIN_CLASS: 2.2.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (tktA1) or (tktA2) or (tktA3) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_Phosphate_Cycle PROTEIN_CLASS: 2.2.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dmsA1 and dmsA2 and dmsB1 and dmsC1) or (dmsA1 and dmsA2 and dmsB2 and dmsC1) or (dmsA1 and dmsC2 and dmsB1 and dmsC1) or (dmsA1 and dmsC2 and dmsB2 and dmsC1) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.8.99.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dmsA1 and dmsA2 and dmsB1 and dmsC1) or (dmsA1 and dmsA2 and dmsB2 and dmsC1) or (dmsA1 and dmsC2 and dmsB1 and dmsC1) or (dmsA1 and dmsC2 and dmsB2 and dmsC1) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.8.99.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP1975) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.1.21 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (deoA) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.4.2.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (thyA) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.1.1.45 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (thiL) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.4.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (thiE) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.5.1.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (tpiA) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 5.3.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (trxB) PROTEIN_ASSOCIATION: SUBSYSTEM: Oxidative_phosphorylation PROTEIN_CLASS: 1.8.1.9 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (treC) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.2.1.93 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ptsH and ptsI and treB) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: 2.7.3.9 and EC-2.7.1.69 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (metC2) or (metC3) PROTEIN_ASSOCIATION: SUBSYSTEM: Cysteine_Metabolism PROTEIN_CLASS: 4.4.1.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (trpA and trpB) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_Tryptophan_and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (trpA and trpB) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_Tryptophan_and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (trpA and trpB) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_Tryptophan_and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aroP1) or (aroP2) or (aroP3) or (mtr) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mmsB) PROTEIN_ASSOCIATION: SUBSYSTEM: Glyoxylate_Metabolism PROTEIN_CLASS: 1.1.1.60 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cysA and cysP and cysT and cysW) or (cysA and sbp and cysT and cysW) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fadL) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (tyrB) PROTEIN_ASSOCIATION: SUBSYSTEM: Phenylalanine_Metabolism PROTEIN_CLASS: 2.6.1.57 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aspC) or (hisC) or (tyrB) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_Tryptophan_and_Phenylalanine_Metabolism PROTEIN_CLASS: 2.6.1.1 or EC-2.6.1.9 or EC-2.6.1.57 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (aroP1) or (aroP2) or (aroP3) or (tyrP) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (lpxD) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (murE) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.3.2.13 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (wecC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 1.1.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (rffE) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 5.1.3.14 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (lpxA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.3.1.129 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (murA) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.5.1.7 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glmU) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.7.7.23 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (murG) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.4.1.227 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (murD) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.3.2.9 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (murC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.3.2.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (murB) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 1.1.1.158 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fre) PROTEIN_ASSOCIATION: SUBSYSTEM: Porphyrin_metabolism PROTEIN_CLASS: 1.16.1.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ubiE) PROTEIN_ASSOCIATION: SUBSYSTEM: Ubiquinone_biosynthesis PROTEIN_CLASS: 2.1.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ubiE) PROTEIN_ASSOCIATION: SUBSYSTEM: Ubiquinone_biosynthesis PROTEIN_CLASS: 2.1.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ubiF) PROTEIN_ASSOCIATION: SUBSYSTEM: Ubiquinone_biosynthesis PROTEIN_CLASS: 1.14.13- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ubiG) PROTEIN_ASSOCIATION: SUBSYSTEM: Ubiquinone_biosynthesis PROTEIN_CLASS: 2.1.1.64 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ubiH) PROTEIN_ASSOCIATION: SUBSYSTEM: Ubiquinone_biosynthesis PROTEIN_CLASS: 1.14.13.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (uppP) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.6.1.27 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (uppS) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.5.1.31 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (galE) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.1.3.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ugd) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 1.1.1.22 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (galT) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.7.12 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (murF) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.3.2.10 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (lpxC) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cmk) or (pyrH) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.14 and EC-2.7.4.22 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (tyrB) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.6.1.57 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cysG) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.1.1.107 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hemD) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.2.1.75 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (hemE) PROTEIN_ASSOCIATION: SUBSYSTEM: Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.1.1.37 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (upp) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.4.2.9 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (uppS) PROTEIN_ASSOCIATION: SUBSYSTEM: Terpenoid_biosynthesis PROTEIN_CLASS: 2.5.1.31 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (uppS) PROTEIN_ASSOCIATION: SUBSYSTEM: Terpenoid_biosynthesis PROTEIN_CLASS: 2.5.1.31 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3918) or (YP4014) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3918) or (YP4014) PROTEIN_ASSOCIATION: SUBSYSTEM: Putative_Transporters PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2473) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2249) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.4.9 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (udk) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.7.1.48 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nupC1) or (nupC2) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP0850) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ilvE) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_leucine_and_isoleucine_metabolism PROTEIN_CLASS: 2.6.1.42 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (livF and livG and livH and livK2 and livM and livK1 and livM2 and livG1 and livF1) or (livF and livG and livH and livK2 and livM1 and livK1 and livM2 and livG1 and livF1) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (brnQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (avtA) PROTEIN_ASSOCIATION: SUBSYSTEM: Alanine_and_aspartate_metabolism PROTEIN_CLASS: 2.6.1.66 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (sgbU) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3918) or (YP4014) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3918) or (YP4014) PROTEIN_ASSOCIATION: SUBSYSTEM: Putative_Transporters PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (gpt and hpt) PROTEIN_ASSOCIATION: SUBSYSTEM: Nucleotide_Salvage_Pathways PROTEIN_CLASS: 2.4.2.22 2.4.2.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (xylA) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.3.1.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (xylA) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.3.1.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (xylB1) or (xylB2) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (araH12 and mglA7 and xylF) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (irp1 and irp2 and ybtE and ybtU) PROTEIN_ASSOCIATION: SUBSYSTEM: Biosynthesis_of_siderophore_group_nonribosomal_peptides PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ybtS) PROTEIN_ASSOCIATION: SUBSYSTEM: Biosynthesis_of_Siderophore_group_nonribosomal_petides PROTEIN_CLASS: YbtS LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (bglX1) or (chb) PROTEIN_ASSOCIATION: SUBSYSTEM: Aminosugars_metabolism PROTEIN_CLASS: 3.2.1.52 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (bglX1) or (chb) PROTEIN_ASSOCIATION: SUBSYSTEM: Sphingolipid_metabolism PROTEIN_CLASS: 3.2.1.52 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (acd) PROTEIN_ASSOCIATION: SUBSYSTEM: Cysteine_Metabolism PROTEIN_CLASS: 4.4.1.15 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP0313) PROTEIN_ASSOCIATION: SUBSYSTEM: Folate_Metabolism PROTEIN_CLASS: 4.2.3.12 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2993) or (aRA11) PROTEIN_ASSOCIATION: SUBSYSTEM: Fructose_and_mannose_metabolism PROTEIN_CLASS: 1.1.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2993) or (aRA11) PROTEIN_ASSOCIATION: SUBSYSTEM: butanoate_metabolism PROTEIN_CLASS: 1.1.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2993) or (aRA11) PROTEIN_ASSOCIATION: SUBSYSTEM: Bile_acid_biosynthesis PROTEIN_CLASS: 1.1.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2993) or (aRA11) PROTEIN_ASSOCIATION: SUBSYSTEM: Bile_acid_biosynthesis PROTEIN_CLASS: 1.1.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fadB) or (fadJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_Leucine_isoleucine_metabolism PROTEIN_CLASS: 1.1.1.35 or EC 1.1.1.31 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cysG) PROTEIN_ASSOCIATION: SUBSYSTEM: Porphyrin_metabolism PROTEIN_CLASS: 1.3.1.76 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cysG) PROTEIN_ASSOCIATION: SUBSYSTEM: Porphyrin_metabolism PROTEIN_CLASS: 4.99.1.4 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (metC2) or (metC3) PROTEIN_ASSOCIATION: SUBSYSTEM: Cysteine_Metabolism PROTEIN_CLASS: 4.4.1.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (metC2) or (metC3) PROTEIN_ASSOCIATION: SUBSYSTEM: Selenoamino_acid_metabolism PROTEIN_CLASS: 4.4.1.8 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (eutG) PROTEIN_ASSOCIATION: SUBSYSTEM: Methane_metabolism PROTEIN_CLASS: 1.1.1.244 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (kdtX and rfaC and rfaF and rfaQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (kdtX and rfaC and rfaF and rfaQ) PROTEIN_ASSOCIATION: SUBSYSTEM: Cell_Envelope_Biosynthesis PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3757 and pelY) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_and_Glucoronate_Interconverstion PROTEIN_CLASS: 3.1.1.11 4.2.2.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mgtA) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: 3.6.1- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mgtA) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: 3.6.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fAA1 and fadA and fadB and fadE) or (fAA1 and fadA and fadJ and fadE) or (fAA1 and fadI and fadB and fadE) or (fAA1 and fadI and fadJ and fadE) or (fadD and fadA and fadB and fadE) or (fadD and fadA and fadJ and fadE) or (fadD and fadI and fadB and fadE) or (fadD and fadI and fadJ and fadE) PROTEIN_ASSOCIATION: SUBSYSTEM: Membrane_Lipid_Metabolism PROTEIN_CLASS: 2.3.1.16 and EC-1.1.1.35 and EC-4.2.1.17 and EC-1.3.99.- and 6.2.1.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (bglB) or (bglX2) PROTEIN_ASSOCIATION: SUBSYSTEM: Starch_and_sucrose_metabolism PROTEIN_CLASS: 3.2.1.21 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (bglB) or (bglX2) PROTEIN_ASSOCIATION: SUBSYSTEM: Cyanamino_acid_metabolism PROTEIN_CLASS: 3.2.1.21 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nudF) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_metabolism PROTEIN_CLASS: 3.6.1.13 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3531 and YP3532 and manX2 and ptsO and ptsP) PROTEIN_ASSOCIATION: SUBSYSTEM: Transport_Extracellular PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3545) or (malZ) PROTEIN_ASSOCIATION: SUBSYSTEM: Galactose_metabolism PROTEIN_CLASS: 3.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3545) or (malZ) PROTEIN_ASSOCIATION: SUBSYSTEM: Starch_and_sucrose_metabolism PROTEIN_CLASS: 3.2.1.20 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3503) PROTEIN_ASSOCIATION: SUBSYSTEM: Polyamine_synthesis PROTEIN_CLASS: 3.5.3.12 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (glsA1) or (glsA2) PROTEIN_ASSOCIATION: SUBSYSTEM: Glutamate_metabolism PROTEIN_CLASS: 3.5.1.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dkgA and dkgB) PROTEIN_ASSOCIATION: SUBSYSTEM: Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.274 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dcd1) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_metabolism PROTEIN_CLASS: 4.1.1.28 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dcd1) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_metabolism PROTEIN_CLASS: 4.1.1.28 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dcd1) PROTEIN_ASSOCIATION: SUBSYSTEM: Phenylalanine_Metabolism PROTEIN_CLASS: 4.1.1.28 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dcd1) PROTEIN_ASSOCIATION: SUBSYSTEM: Tryptophan_Metabolism PROTEIN_CLASS: 4.1.1.28 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dcd1) PROTEIN_ASSOCIATION: SUBSYSTEM: Tryptophan_Metabolism PROTEIN_CLASS: 4.1.1.28 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dcd1) PROTEIN_ASSOCIATION: SUBSYSTEM: Tryptophan_Metabolism PROTEIN_CLASS: 4.1.1.28 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (acyP) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 3.6.1.7 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (acyP) PROTEIN_ASSOCIATION: SUBSYSTEM: Pyruvate_metabolism PROTEIN_CLASS: 3.6.1.7 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (pksG) PROTEIN_ASSOCIATION: SUBSYSTEM: butanoate_metabolism PROTEIN_CLASS: 2.3.3.10 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (adhC) or (adhE) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycolysis/Gluconeogenesis PROTEIN_CLASS: 1.1.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (adhC) PROTEIN_ASSOCIATION: SUBSYSTEM: Methane_metabolism PROTEIN_CLASS: 1.1.1.284 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (adhC) or (adhE) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_metabolism PROTEIN_CLASS: 1.1.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (adhC) or (adhE) PROTEIN_ASSOCIATION: SUBSYSTEM: Bile_acid_biosynthesis PROTEIN_CLASS: 1.1.1.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mhpD2) or (ysuJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Pyruvate_metabolism PROTEIN_CLASS: 4.1.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mhpD2) or (ysuJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_metabolism PROTEIN_CLASS: 4.1.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mhpD2) or (ysuJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_metabolism PROTEIN_CLASS: 4.1.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mhpD2) or (ysuJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_metabolism PROTEIN_CLASS: 4.1.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mhpD2) or (ysuJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Tryptophan_Metabolism PROTEIN_CLASS: 4.1.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mhpD2) or (ysuJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Aminophosphonate_metabolism PROTEIN_CLASS: 4.1.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mhpD2) or (ysuJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Ascorbate_and_aldarate_metabolism PROTEIN_CLASS: 4.1.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mhpD2) or (ysuJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Ascorbate_and_aldarate_metabolism PROTEIN_CLASS: 4.1.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mhpD2) or (ysuJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Flourene_degradation PROTEIN_CLASS: 4.1.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mhpD2) or (ysuJ) PROTEIN_ASSOCIATION: SUBSYSTEM: Nitrogen_Metabolism PROTEIN_CLASS: 4.1.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mhpD2) PROTEIN_ASSOCIATION: SUBSYSTEM: Tyrosine_metabolism PROTEIN_CLASS: .5.3.3.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mhpD2) PROTEIN_ASSOCIATION: SUBSYSTEM: Flourene_degradation PROTEIN_CLASS: 5.3.3.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nagC4) PROTEIN_ASSOCIATION: SUBSYSTEM: aminosugars_metabolism PROTEIN_CLASS: 2.7.1.59 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (appA) PROTEIN_ASSOCIATION: SUBSYSTEM: Inositol_phosphate_metabolism PROTEIN_CLASS: 3.1.3.26 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (appA) PROTEIN_ASSOCIATION: SUBSYSTEM: Thiamine_metabolism PROTEIN_CLASS: 3.1.3.2 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP1994 and tesA and tesB) PROTEIN_ASSOCIATION: SUBSYSTEM: Limonene_and_Pinene_degradation PROTEIN_CLASS: 3.1.2.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (csdB1) PROTEIN_ASSOCIATION: SUBSYSTEM: Selenoamino_acid_metabolism PROTEIN_CLASS: 4.4.1.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (leuB1) PROTEIN_ASSOCIATION: SUBSYSTEM: Glyoxylate_and_dicarboxylate_metabolism PROTEIN_CLASS: 1.1.1.93 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (leuB1) PROTEIN_ASSOCIATION: SUBSYSTEM: Glyoxylate_and_dicarboxylate_metabolism PROTEIN_CLASS: 1.1.1.93 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (leuB1) PROTEIN_ASSOCIATION: SUBSYSTEM: butanoate_metabolism PROTEIN_CLASS: 1.1.1.83 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (mhpC3) PROTEIN_ASSOCIATION: SUBSYSTEM: Ubiquinone_biosynthesis PROTEIN_CLASS: 3.1.2.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (putA1) PROTEIN_ASSOCIATION: SUBSYSTEM: Propanoate_metabolism PROTEIN_CLASS: 1.2.1.27 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (ilvB1) PROTEIN_ASSOCIATION: SUBSYSTEM: Inositol_metabolism PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (putA1) PROTEIN_ASSOCIATION: SUBSYSTEM: Inositol_metabolism PROTEIN_CLASS: 1.2.1.27 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (iolE) PROTEIN_ASSOCIATION: SUBSYSTEM: Inositol_metabolism PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP1128) or (rbsK2) PROTEIN_ASSOCIATION: SUBSYSTEM: Inositol_metabolism PROTEIN_CLASS: 2.7.1.92 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2370) or (surE) PROTEIN_ASSOCIATION: SUBSYSTEM: Nicotinate_and_nicotinamide_metabolism PROTEIN_CLASS: 3.1.3.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2370) or (surE) PROTEIN_ASSOCIATION: SUBSYSTEM: Nicotinate_and_nicotinamide_metabolism PROTEIN_CLASS: 3.1.3.5 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2500) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_metabolism PROTEIN_CLASS: 3.1.4.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP2500) PROTEIN_ASSOCIATION: SUBSYSTEM: Purine_metabolism PROTEIN_CLASS: 3.1.4.17 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fadA) or (fadI) PROTEIN_ASSOCIATION: SUBSYSTEM: Valine_Leucine_isoleucine_metabolism PROTEIN_CLASS: 2.3.1.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fadA) or (fadI) PROTEIN_ASSOCIATION: SUBSYSTEM: Bile_acid_biosynthesis PROTEIN_CLASS: 2.3.1.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fadA) or (fadI) PROTEIN_ASSOCIATION: SUBSYSTEM: Bile_acid_biosynthesis PROTEIN_CLASS: 2.3.1.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fadA) or (fadI) PROTEIN_ASSOCIATION: SUBSYSTEM: Bile_acid_biosynthesis PROTEIN_CLASS: 2.3.1.16 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (racX) PROTEIN_ASSOCIATION: SUBSYSTEM: alanine_and_aspartate_metabolism PROTEIN_CLASS: 5.1.1.3 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nanE) PROTEIN_ASSOCIATION: SUBSYSTEM: Aminosugars_metabolism PROTEIN_CLASS: 5.1.3.9 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP0738) PROTEIN_ASSOCIATION: SUBSYSTEM: Pantothenate_and_CoA_metabolism PROTEIN_CLASS: 3.1.4.14 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (nagC1) PROTEIN_ASSOCIATION: SUBSYSTEM: fructose_and_mannose_metabolism PROTEIN_CLASS: 2.7.4.1 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (dAK12) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycerolipid_Metabolism PROTEIN_CLASS: 2.7.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (wecF1) PROTEIN_ASSOCIATION: SUBSYSTEM: Glycerolipid_Metabolism PROTEIN_CLASS: 2.4.1.- LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (fba) or (fbaA) PROTEIN_ASSOCIATION: SUBSYSTEM: Pentose_and_Glucoronate_Interconverstion PROTEIN_CLASS: 4.1.2.13 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (cysK1) or (cysK2) or (cysM) or (cysM2) PROTEIN_ASSOCIATION: SUBSYSTEM: Selenoamino_acid_metabolism PROTEIN_CLASS: 2.5.1.47 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: (YP3998) PROTEIN_ASSOCIATION: SUBSYSTEM: Arginine_and_Proline_Metabolism PROTEIN_CLASS: 4.3.1.12 LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: LOWER_BOUND UPPER_BOUND OBJECTIVE_COEFFICIENT FLUX_VALUE REDUCED_COST